Anti-Inflammatory Blueberry Smoothie (Paleo Keto) – packed with anti-inflammatory ingredients, this drink is a refreshing powerhouse and a great way to start your day!

There’s nothing better than a cool, fruity smoothie for breakfast or a snack.  I have plenty of favorite combos, but when it comes to taste and nutritional benefits, this Anti-Inflammatory Smoothie is my favorite.  With only four ingredients, it’s a simple and quick way to add some superfoods to your diet.  And of course it’s super delicious too!

This smoothie is great for fighting inflammation as a regular addition to your diet but I also add it to my morning routine whenever I feel like I’ve gotten a little off track (hello holiday overindulging.)  It’s so refreshing and cleansing, and has those detoxifying powers I need.  Not to mention it’s bursting with flavor and there are tons of fun ways to change it up (see below.)  If you’re mornings are hectic, this is a great option – just dump in the blender, blend, and go!

What is Inflammation?

We tend to think of inflammation as all bad but in reality it is a necessary response triggered by our immune system to fight infection, injury, or disease. Inflammation becomes a problem when it is chronic over long periods of time. In fact, too much inflammation is often the root of disease such as cancer, heart disease, and Type 2 Diabetes.

Inflammation can be caused by many conditions and triggers, but our diet and the food we consume is certainly a big one. Fortunately, it’s also one that’s within our control! We can maintain a healthy balance of inflammation in our bodies by limiting sugar, trans fats, alcohol, and other processed foods and upping our intake of foods dense in antioxidants.

I’m a firm believer that food can be medicine. It’s a known fact our bodies respond positively or negatively to what we put in them.  When I eat junk, I feel lethargic, bloated, and generally yucky.  When I eat well, I feel energized, clear minded, and strong. So as much as possible, it makes sense to fight inflammation where we can by using our diet.

Examples of Anti-Inflammatory Foods

  • berries and cherries
  • tomatoes and orange bell peppers
  • green leafy vegetables, such as spinach, kale, collards
  • walnuts and flax
  • fatty fish like salmon, mackerel, tuna, and sardines
  • green tea
  • broccoli
  • spices, like turmeric and cloves

Pro Tips for Making Anti-Inflammatory Blueberry Smoothie

Double the recipe and pour extra into silicone ice cube trays, then blend frozen cubes for a quick smoothie on the go.

Store individual servings of prepped ingredients in a Ziploc in the freezer.  Just dump in blender and add liquid.

Pour into popsicle molds and freeze for a yummy frozen treat.

Use your choice of liquid in place of water.  Almond milk and coconut water are great choices.

Use kale instead of spinach, or a mix of both.

Add 1/4 of a large banana for a little extra sweetness.

To add some extra healthy fats, add a tablespoon of almond butter.

More Anti-Inflammatory Recipes

Make Ahead Smoothie Packets

Instant Pot Detox Turmeric Veggie Soup

Detox Chopped Salad with Garlic Lemon Vinaigrette

Easy Cream of Broccoli Soup

top down of anti-inflammatory blueberry smoothie

anti-inflammatory blueberry smoothie in mason jar

whole30 anti-inflammatory blueberry smoothie

anti-inflammatory blueberry smoothie in mason jar

Anti-Inflammatory Blueberry Smoothie (Paleo)

Anti-Inflammatory Blueberry Smoothie (Paleo) - packed with anti-inflammatory ingredients, this drink is a refreshing powerhouse and a great way to start your day!
4.75 from 4 votes


  • 3/4 cup frozen blueberries, or fresh
  • 4-5 large strawberries
  • 1 cup packed spinach leaves
  • 1 tablespoon flaxseed meal
  • 3/4 cup water or almond milk


  • Combine all ingredients in a blender and process until completely smooth.  
  • If desired, pour smoothie into popsicle molds or ice cube trays and freeze for future use.


Note: nutrition facts calculated using water as the added liquid.


Calories: 142kcal, Carbohydrates: 27g, Protein: 4g, Fat: 4g, Saturated Fat: 1g, Sodium: 28mg, Potassium: 475mg, Fiber: 7g, Sugar: 17g, Vitamin A: 2873IU, Vitamin C: 83mg, Calcium: 65mg, Iron: 2mg

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